IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner
IGF-1LR3 and Hypertrophy Myostatin, also known as growth differentiation factor 8, is an important protein that regulates muscle growth and development
Gut microbiome dysbiosis across early Parkinsons disease, REM sleep behavior disorder and their first-degree relatives
Berberine is a plant alkaloid sold as an unregulated food supplement in the UK, not a licensed medicine approved by the MHRA It may enhance blood glucose-lowering effects of diabetes medications, increasing hypoglycaemia risk, particularly with insulin and sulphonylureas Potential interactions with anticoagulants (warfarin, DOACs) require specialist advice and may necessitate more frequent INR monitoring Berberine may increase blood levels of statins, immunosuppressants, and other CYP3A4-metabolised drugs, raising toxicity risks Always consult your GP before starting berberine if taking any prescription medications, pregnant, breastfeeding, or have liver or kidney disease Stop berberine at least 2 weeks before planned surgery and report any suspected side effects via the MHRA Yellow Card Scheme Table of Contents What Is Berberine and How Does It Work
